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Tumor Cell Lines

SH-SY5Y

  • BSL

    1

  • 111
Tumorigenecity: Isoenzyme: Histopathology: Subculture: Split ratio: Media change: Reverse transcritase: Production.
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  • High Purity Levels
  • Precision and Reliability
  • Customization Options

Human neuroblastoma cell line SH-SY5Y is a subline of the SK-N-SH cells, which was established in culture in 1970 from a bone marrow biopsy of a metastatic neuroblastoma of a 4-year-old female and has undergone three rounds of clonal selection.
This is a relatively homogeneous neuroblast-like cell line. The initial characterization of the SH-SY5Y cell line showed moderate activity of dopamine-β-hydroxylase and negligible levels of choline acetyl-transferase, acetylcholinesterase and butyryl-cholinesterase, basal noradrenaline (NA) release and tyrosine hydroxylase activity. In addition, SH-SY5Y neuroblastoma cells also express opioids, muscarinic and nerve growth factor receptors.

Why choose SH-SY5Y from AcceGen?
All SH-SY5Y cells are stored frozen in the cell culture kit. Each vial contains > 5×10^5 cells or can be customized according to requirements. All cells are tested negative for mycoplasma, bacteria, yeast, and fungi.
We provide customers with the best training program optimized by our technicians. If you have any questions, technical service representatives are available to answer your product questions timely.
Our cell products are of high purity, easy to obtain, and could be used in scientific research and laboratories.

Product Code

SH-Sy5y; SHSY5Y; SHSY-5Y; SK-SH-SY5Y; SY5Y; SH-SY5Y Parental

Species

Human

Cat.No

ABC-TC1019

Product Category Tumor Cell Lines
Size/Quantity

1 vial

Cell Type

Epithelial

Shipping Info

Dry Ice

Growth Conditions

37 ℃, 5% CO2

Source Organ

Brain

Disease

Neuroblastoma

Biosafety Level

1

Storage

Liquid Nitrogen

Product Type

Human Bone Marrow Neuroblast Cell Lines

Citation

When you publish your research, please cite our product as “AcceGen Biotech Cat.# XXX-0000”. In return, we’ll give you a $100 coupon. Simply click here and submit your paper’s PubMed ID (PMID).

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Application

  • For research use only

  • Based on its human origin, catecholaminergic neuron characteristics, and easy maintenance, SH-SY5Y neuronal cells are widely used in laboratory medical scientific research:
  • -Establish neurological disorders models, such as Parkinson’s Disease (PD)
  • -Drug screening
  • -Neuroprotection and neurotoxicity assay
  • -Co-culture with other neuron cells
  • -Study neural development and signaling
  • -Research on the Mechanism of Nervous System Diseases

Inquiring SH-SY5Y

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High Viability
To succeed in cell culture
Precision and Reliability
To support a consistent result
Customization Options
Tailed to your research

Tags

  • Bone Marrow (115)
  • Human (1729)
  • Neuroblast (6)
  • Normal (1578)
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