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Human Urothelial Cells | ||||
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| Product Name | Human Urothelial Cells | |||
| Price | Get Quote | |||
| Product Code | HUC | |||
| Cat.No | ABC-TC3861 | Species | Human | |
| Size/Quantity | 1 vial | Biosafety Level | 1 | |
| Shipping Info | Dry Ice | Storage | Liquid Nitrogen | |
| Description | Human urothelial cells are a specialized cell type that lines the inner surface of the urinary bladder, exhibiting remarkable plasticity and diverse functions. Serving as the primary defense barrier within the bladder, they act as a crucial interface against invading pathogens.
Why choose Human Urothelial Cells from AcceGen? AcceGen’s Human Urothelial Cells, derived from the human bladder, are cryopreserved at passage one, with over 5×105 cells per 1 ml vial. These cells were identified through immunofluorescence using cytokeratin-18 and/or cytokeratin-19-specific antibodies. They are free of HIV-1, HBV, HCV, mycoplasma, bacteria, yeast, and fungi. They can be expanded for up to 15 population doublings under the conditions provided by AcceGen, rendering them excellent for research purposes. | |||
| Disease | Normal | |||
| Source Organ | Urothelial | |||
| Quality Control | All cells test negative for mycoplasma, bacteria, yeast, and fungi. | |||
| Recommended Medium And Supplement | ABM-TM3861 Human Urothelial Cells Medium Kit | |||
| Citation Guide | When you publish your research, please cite our product as “AcceGen Biotech Cat.# XXX-0000”. In return, we’ll give you a $100 coupon. Simply click here and submit your paper’s PubMed ID (PMID). | |||
| Application | FOR RESEARCH USE ONLY Human urothelial cells offer a valuable resource for various applications. Their in vitro cultivation enables the exploration of urothelial cell immunoregulatory capabilities. Moreover, they serve as essential tools for the development of in vitro disease models, particularly for high throughput and high content screening. Additionally, these cells establish a foundation for investigating proliferation, stratification, and differentiation within epithelia, positioning urothelium as a versatile in vitro model for research in these areas. | |||
| Growth Conditions | 37 ℃, 5% CO2 | |||
| Cell Type | Urothelial Cell | |||
| Growth Mode | Adherent | |||
| Product Type | Urethral Cells | |||
| Product Image |  | |||
These cells employ an array of defense mechanisms to thwart pathogen adherence and maintain the impermeability of the bladder to urinary solutes. Expressing key receptors such as estrogen receptor-alpha, estrogen receptor-beta, epidermal growth factor receptor, and fibroblast growth factor receptor, urothelial cells play a pivotal role in responding to injuries and infections. Additionally, they release various cytokines and immune system mediators, contributing to the overall immune defense of the urinary system.- ONLINE INQUIRY
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