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MDCK Derivation and Characters
Madin-Darby Canine Kidney cells (MDCK) are derived from kidney of normal female adult Cocker Spaniel canine. At first, MDCK heterogeneous was noticed due to the variable morphology, chromosome number from different laboratories analysis result. MDCK cells are then characterized by their growth, immunologic and cytogenetic properties, as well as their susceptibility to several viruses.
Why Choose MDCK from AcceGen?
AcceGen MDCK cells are suitable for simulating epithelial tissue in vitro, as their high apico-basolateral polarity and tight junctions. MCDK and its sub-clones play important roles in epithelial cell trafficking, cell polarity and tight junctions. MDCK cell line is also a good choice for virus study and vaccine development.
| Product Code | MDCK (NBL-2); NBL-2; Madin-Darby Canine Kidney; Madin Darby Canine Kidney |
| Species | Dog |
| Cat.No | ABL-TC0399 |
| Product Category | Tumor Cell Lines |
| Size/Quantity | 1 vial |
| Cell Type | Epithelial |
| Shipping Info | Dry Ice |
| Growth Conditions | 37 ℃, 5% CO2 |
| Source Organ | Kidney |
| Disease | Normal |
| Biosafety Level | 1 |
| Storage | Liquid Nitrogen |
| Product Type | Canine Kidney Cell Lines |
When you publish your research, please cite our product as “AcceGen Biotech Cat.# XXX-0000”. In return, we’ll give you a $100 coupon. Simply click here and submit your paper’s PubMed ID (PMID).
For research use only
In the last few decades, MDCK cells were found to proliferate, form hollow tubules in monolayers and respond to the added collagen. Such discoveries suggest the possibility of a MDCK 3D culture.
Moreover, several strains with different resistive and transport properties have been derived from MDCK for different research purposes.
