COS-7
1
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COS-7 cells, derived from the CV-1 African green monkey fibroblast cell line, are a commonly used type of COS cell line. Established in 1981 by Professor Yakov Gluzman, they were created through the transformation of CV-1 cells using a mutant strain of Simian Virus 40 (SV40) that encodes the wild-type T-antigen. These cells closely resemble human fibroblast cells and are often referred to as COS-7 monkey fibroblast or COS-7 fibroblast-like cells. In culture, COS-7 cells exhibit adherent growth on glass and plastic surfaces, displaying a fibroblast-like morphology. Due to the transformation process, COS-7 cells express SV40 T-antigen and remain susceptible to SV40, allowing lytic growth within the kidney cells.
Why choose COS-7 from AcceGen?
COS-7 cells from AcceGen are a preferred choice due to several factors. They are provided in a sterile form and are confirmed to be free from mycoplasma contamination. AcceGen ensures daily visual checks for the presence of bacteria and fungi to maintain cell integrity. The cells are incubated under optimal and standardized conditions by professional operators. Additionally, rigorous quality control measures are implemented to guarantee reliable and high-quality COS-7 cell lines.
| Product Code | Cos-7; COS 7; Cos 7; COS7; Cos7; CV-1 in Origin Simian-7 |
| Species | Cercopithecus Aethiops |
| Cat.No | ABC-TC0190 |
| Product Category | Tumor Cell Lines |
| Size/Quantity | 1 vial |
| Cell Type | Fibroblast-like |
| Shipping Info | Dry Ice |
| Growth Conditions | 37 ℃, 5% CO2 |
| Source Organ | Kidney |
| Biosafety Level | 1 |
| Storage | Liquid Nitrogen |
| Product Type | Monkey Kidney Cell Lines |
When you publish your research, please cite our product as “AcceGen Biotech Cat.# XXX-0000”. In return, we’ll give you a $100 coupon. Simply click here and submit your paper’s PubMed ID (PMID).
FOR RESEARCH USE ONLY
COS-7 cells find multiple applications in research. They are widely utilized for studying SV40 monkey viruses and serve as the commonly used mammalian production cells for synthesizing recombinant proteins like antibodies and signaling molecules. The fibroblastic-like growth characteristics of COS-7 cells, combined with their susceptibility to SV40, make them an excellent choice for transfection experiments involving DNA plasmids and mutations to the SV40 virus. Given the potential link between SV40 and human cancers, the continued use of COS-7 cells in SV40-related research contributes to our understanding of these diseases.
