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Rat Cardiac Microvascular Endothelial Cells (RCMEC) are derived from rat heart tissue and play pivotal roles in myocardial function. These specialized cells are responsible for regulating vascular tone by releasing and breaking down endothelium-derived vasoactive factors, thus modulating the levels of vasoconstrictors and vasodilators through enzymatic processes. This intricate control extends to influencing myocardial contractile behavior. Beyond vascular function, RCMEC are integral in regulating leukocyte recruitment, inflammation, and angiogenesis within the microvasculature. Notably, they exhibit the ability to trans-differentiate into myofibroblasts, hinting at their involvement in matrix accumulation and fibrotic disorders. RCMEC express key markers such as vWF/Factor VIII and CD31 (PECAM).
Why choose Rat Cardiac Microvascular Endothelial Cells from AcceGen?
AcceGen’s Rat Cardiac Microvascular Endothelial Cells (RCMEC) are cryopreserved at passage one and shipped in a frozen state, ensuring their viability upon arrival. Each vial of RCMEC contains over 0.5×106 viable cells, and they are guaranteed to expand for up to 5 population doublings when following the provided technical sheet instructions, making them a reliable and versatile resource for research purposes.
Product Code | RCMEC |
Species | Rat |
Cat.No | ABC-TC4108 |
Quality Control | All cells test negative for mycoplasma, bacteria, yeast, and fungi. |
Product Category | Primary Cells |
Size/Quantity | 1 vial |
Cell Type | Endothelial |
Shipping Info | Dry Ice |
Growth Conditions | 37 ℃, 5% CO2 |
Source Organ | Heart |
Disease | Normal |
Biosafety Level | 1 |
Storage | Liquid Nitrogen |
Product Type | Rat Primary Cells |
When you publish your research, please cite our product as “AcceGen Biotech Cat.# XXX-0000”. In return, we’ll give you a $100 coupon. Simply click here and submit your paper’s PubMed ID (PMID).
FOR RESEARCH USE ONLY
Rat Cardiac Microvascular Endothelial Cells (RCMEC) serve as a crucial asset for delving into the physiological and pathophysiological aspects of cardiac microvascular endothelium. These cells facilitate a deeper exploration of the intricacies of the cardiac microvasculature, offering insights into the pathophysiology of inflammatory cardiomyopathies and their implications. By studying RCMEC, researchers can unravel critical information concerning their role in cardiac function and disease, ultimately contributing to a better understanding of these complex cardiovascular conditions.