CD57 Mouse Microglia

Mouse microglia are a vital component of the neuro-glial cell network in the central nervous system (CNS). They are present in the brain parenchyma from early development to maturity. These microglia perform crucial functions in brain immune surveillance. Sharing common antigens with hematopoietic and tissue macrophages, they act as brain macrophages upon activation, clearing tissue debris, damaged cells, or microbes during brain development or CNS injury. Microglia interact with neurons and other glial cells, producing biologically active substances like growth factors and cytokines. They play a crucial role in various physiological and pathological processes in the brain. Originating from hematopoietic stem cells in the bone marrow, microglia are resident macrophages, actively surveying the CNS and contributing to neurodevelopment, plasticity, repair, inflammation, aging, neurodegeneration, neuropathic pain, and infections.

Why choose CD57 Mouse Microglia from AcceGen?

Mouse microglia possess important features that contribute to their suitability for research. These include a sterile environment, ensuring the absence of bacterial, fungal, and mycoplasma contamination. They exhibit high viability, which is crucial for reliable experimentation. Professional handling under optimal conditions ensures the maintenance of their functional properties. Rigorous quality control measures are implemented to verify their purity and integrity. These combined features guarantee the reliability, reproducibility, and quality of mouse microglia cultures, making them valuable tools for scientific investigations.