C57BL/6 Mouse Esophageal Epithelial Cells

C57BL/6 Mouse esophageal epithelial cells are primary cells derived from the esophageal epithelium of wild-type C57BL/6 mice. The esophagus of these mice is characterized by a keratinized layer on its surface. This tissue is known for its rapid turnover, although conflicting findings have made it challenging to determine the presence of a distinct stem cell population responsible for cellular renewal. The cellular organization within the mouse esophagus is heterogeneous, comprising actively proliferating stem cells alongside more differentiated transit-amplifying cells. The self-renewal process in the esophagus is regulated by Sox2, Wnt, and bone morphogenetic protein signaling pathways, which play vital roles in maintaining the integrity and functionality of these esophageal epithelial cells.

Why choose C57BL/6 Mouse Esophageal Epithelial Cells from AcceGen?

C57BL/6 mouse esophageal epithelial cells from AcceGen are the preferred choice due to their high viability and strict sterility, ensuring a reliable and contamination-free experimental environment. These cells are characterized by immunofluorescent staining using specific antibodies such as E-cadherin or ZO-1, enabling precise identification and analysis of cell markers. Moreover, these cells can be easily expanded for multiple passages, allowing for extended experimentation and flexibility in research. AcceGen provides detailed and specific cell culture conditions for optimal growth and maintenance, further ensuring the quality and consistency of the cell line throughout experiments.