Primary cells are isolated from fresh tissues, which can maintain the basic properties of the original cells. Therefore, as an in vitro experimental model, primary cells are widely used in basic research of molecular, cell biology and biomedicine, such as proteomics, genomics and genetics, and also in drug screening, drug metabolism and toxicology, cancer drug research, etc. AcceGen provides 1,278 kinds of primary cells from human and animals, including human primary cells from motor system, nervous system, endocrine system, digestive system, blood system, urinary system, reproductive system, immune system, respiratory system, and PBMCs; and animal primary cells from mouse, rat, bovine, monkey, rabbit, porcine, chicken, dog, cat, and horse.

Tumor cell lines, also called Cancer cell lines, are an important part of tumors, they are the main component of tumors and tissue specific. Cancer cells have three important basic characteristics: immortality, migration, and loss of contact inhibition. In addition, carcinoma cells have many physiological, biochemical, and morphological characteristics that are different from normal cells. Different cancer cell lines provide a wide range of experimental materials for studying the occurrence and development of tumors and have played an important role in the in-depth study of tumor immunotherapy, tumor-targeted therapy, and tumor resistance.

Transfected Stable Cell Lines is an important research tool for pharmaceutical drug discovery, compound screening, and gene therapy research. The transfected stable cell lines are constructed by integrating the exogenous plasmid DNA into the host cell chromosome so that the host cell can express the protein of interest for a long period of time. Key Features of AcceGen Transfected Stable Cell Lines: ● The exogenous fragment can be stably expressed in dividing cells for a long time (> 2 weeks). ● Establishing stable cell lines can help screen appropriate number of cells for experimental research. ● By establishing stable cell lines, the cost of excessive conversion of dyes or virus packaging can be greatly reduced, and experimental research is greatly facilitated. ● Establishing stable cell lines can achieve better genetic interference effects. ● It can effectively eliminate the interference of individual differences (the same type of cells, different individual cell genomes) on the experimental results. AcceGen is committed to providing ready-to-go stable cell lines and knockout cell lysate for your basic research. Use the Mutant Gene Nomenclature to search, if you cannot find the specific product in our database, AcceGen Custom Stable Cell Lines Service is committed to pave new ways to meet all your needs.

After the primary cells experience limited population proliferation during the culture process, the primary cells cease to proliferate. Immortalized cells are derived from primary cells: exogenous immortalized genes (EBV, HPV E6 / 7 and SV40 T antigens of recombinant lentivirus, retrovirus & adenovirus, hTERT, p53) are introduced into target cells by gene transfection technology and immortalized cell lines are established to achieve cell culture in vitro so that cells cultured in vitro have the ability to proliferate and there is no difference between cells. Through immortalization, those cells that are difficult to pass down, slow to proliferate, and easy to age can be immortalized, thereby providing researchers with more cell resources and providing a good in vitro cell model for scientific research. AcceGen has about 60 kinds of immortalised cell lines, including human immortalised cells, mouse immortalised cells, and rat immortalised cells. AcceGen also provides Custom Cell Immortalization Service for your unique solutions.

Stem Cells, also calls Progenitor Cells, are a kind of self-replicating pluripotent cells, which can differentiate into multiple functional cells under certain conditions. Given this characteristic, some diseases can be cured by transplanting stem cells or related derivatives into patients to replace damaged cells. Stem cells have become the frontier and hotspot of life science and medical research at the beginning of this century because of the broad application prospects in the fields of disease treatment and regenerative medicine.

MicroRNA (miRNA) is a type of endogenous small RNA with a length of about 20-24 nucleotides. A combination of several miRNAs can be used to fine-tune the expression of a gene. MicroRNA Agomir is a special-labeled and chemically modified double-stranded small RNA that mimics the endogenous miRNA to regulate the biological function of the target gene. MicroRNA Antagomir is an especially chemically modified miRNA antagonist. It strongly competes with mature miRNAs in the body to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning. NOMENCLATURE 1. The miRNA mature body is abbreviated as miR, and then according to its species name, such as the human being abbreviated as hsa, and the order in which it was found is represented by Arabic numerals, such as hsa-miR-122. 2. Highly homologous miRNAs are followed by lowercase letters (a, b, c, ...), such as hsa-miR-34a, hsa-miR-34b, hsa-miR-34c, and so on. 3. MiRNAs with the same mature sequence are transcribed and processed from DNA sequences on different chromosomes, followed by Arabic numerals to indicate the difference, such as hsa-miR-199a-1 and hsa-miR-199a-2. 4. Generally, a miRNA precursor is about 70-80nt in length. It is likely that miRNAs are generated by the two arms, and they are named by "-5p" and "-3p". For example, hsa-miR-26b-5p and hsa-miR-26b-3p indicate that they are processed from the 5 'end arm and 3' end arm of the hsa-mir-26b precursor, respectively. AcceGen is committed to providing ready-to-use MicroRNA Agomir/Antagomir for your basic research. Use the Standard Nomenclature to search, if you cannot find the specific product in our database, AcceGen MicroRNA Agomir/Antagomir Synthesis Service is committed to paving new ways to meet all your needs.